Search results for "Reference range"

showing 10 items of 17 documents

Reference interval of monocyte distribution width (MDW) in healthy blood donors.

2020

Abstract Background The aim of the study was to accurately establish the reference interval (RI) of monocyte distribution width (MDW) in healthy blood donors by the direct method using different statistical approaches. Methods MDW was measured in 486 subjects. RI of MDW was calculated by the non-parametric method, the robust method and, the Harrell-Davis bootstrap method and using different tests to identify potential outliers (Dixon-Reed and Tukey). Results Lower and upper reference limits of the RI calculated by the non-parametric method were, 16.22 (90%CI 15.78–16.47) – 23.15 (90%CI 22.80–24.10) (without outlier removal), and 16.44 (90%CI 16.21–16.67) – 22.99 (90%CI 22.33–23.22) (after o…

0301 basic medicine2019-20 coronavirus outbreakSepsiOutlier removalClinical BiochemistryReference rangeBlood DonorsInterval (mathematics)BiochemistryMonocytesReference interval03 medical and health sciences0302 clinical medicineMDWReference ValuesNormal valuesStatisticsHumansMathematicsDirect methodBiochemistry (medical)Direct methodGeneral MedicineReference rangeCalculation methods030104 developmental biologyDistribution (mathematics)Research Design030220 oncology & carcinogenesisOutlierClinica chimica acta; international journal of clinical chemistry
researchProduct

Age-dependent control of collagen-dependent platelet responses by thrombospondin-1 : Comparative analysis of platelets from neonates, children, adole…

2021

Platelet function is developmentally regulated. Healthy neonates do not spontaneously bleed, but their platelets are hypo-reactive to several agonists. The mechanisms underlying immature platelet function in neonates are incompletely understood. This critical issue remains challenging for the establishment of age-specific reference ranges. In this study, we evaluated platelet reactivity of five pediatric age categories, ranging from healthy full-term neonates up to adolescents (11–18 years) in comparison to healthy adults (&gt

0301 basic medicinecollagenAgingMedizin030204 cardiovascular system & hematologyImmature PlateletThrombospondin 10302 clinical medicinePlateletBiology (General)ChildSpectroscopyCD63medicine.diagnostic_testGeneral MedicineComputer Science ApplicationsAdenosine DiphosphateChemistryplateletsAgonistAdultBlood Plateletsmedicine.medical_specialtyAdolescentmedicine.drug_classQH301-705.5Receptors Proteinase-ActivatedCatalysisExocytosisArticleFlow cytometryInorganic Chemistry03 medical and health sciencesInternal medicineThrombospondin 1Crotalid VenomsmedicineHumansLectins C-TypePlatelet activationPhysical and Theoretical Chemistrythrombospondin-1Molecular BiologyQD1-999business.industryflow cytometryOrganic ChemistryInfant NewbornFibrinogen bindingInfantPlatelet Activationreference rangesneonates030104 developmental biologyEndocrinologybusinessPeptides
researchProduct

Differences in serum zinc levels in acutely ill and remitted adolescents and young adults with bulimia nervosa in comparison with healthy controls &a…

2017

Neuropsychiatric disease and treatment 2017(13), 2621-2630 (2017). doi:10.2147/NDT.S137549

050103 clinical psychologymedicine.medical_specialtyNeuropsychiatric Disease and Treatment610bulimia nervosaReference rangeeating disordersGastroenterology03 medical and health sciencesremission0302 clinical medicineInternal medicineMedicineserum concentrations0501 psychology and cognitive sciencesddc:610Young adultOriginal ResearchSerum zincbusiness.industryBulimia nervosazinc05 social sciencesSerum concentrationmedicine.disease030227 psychiatryEating disordersEndocrinologyAnorexia nervosa (differential diagnoses)Prospective researchbusinessNeuropsychiatric Disease and Treatment
researchProduct

Maternal copper status and neuropsychological development in infants and preschool children.

2019

Introduction: Copper (Cu) is an essential element involved in biological processes; however, excessive Cu could be harmful because of its reactive nature. Very few studies have evaluated its potential neurotoxic effects. We aimed to evaluate the association between maternal Cu levels and children's neuropsychological development. Methods: Study subjects were mother-child pairs from the Spanish INMA (i.e. Childhood and Environment) Project. Cu was measured by inductively coupled plasma mass spectrometry in serum samples taken at the first trimester of pregnancy (2003-2005). Neuropsychological development was assessed using the Bayley Scales of Infant Development (BSID) at 12 months (n = 651) a…

AdultMaleMultivariate analysisCognitiveNeurodevelopmentBirth cohort Cognitive Delayed effects Metal Neurodevelopment Prenatal exposureReference rangeDelayed effects010501 environmental sciencesNeuropsychological Tests01 natural sciencesBayley Scales of Infant Development03 medical and health sciences0302 clinical medicineChild DevelopmentPregnancyPrenatal exposureMedicineHumans030212 general & internal medicineChildMaternal-Fetal Exchange0105 earth and related environmental sciencesPsychomotor learningPregnancybusiness.industryMetalPublic Health Environmental and Occupational HealthNeuropsychologyInfantCognitionmedicine.diseaseConfidence intervalcognitive neurodevelopmentPregnancy Trimester Firstmetal delayed effectsChild PreschoolPrenatal Exposure Delayed EffectsFemalebusinessBirth cohortCopperClinical psychologyInternational journal of hygiene and environmental health
researchProduct

Postoperative Reduction of Fibrinolysis as a Prognostic Factor of Fatal Outcome

2001

For the resection of an esophagus carcinoma a mortality rate of 2 to 30% was described, It is still unclear whether an abdominothoracic or transhiatal intervention is superior regarding the outcome. To investigate the prognostic value of fibrinolytic markers, plasmin-α2-antiplasmin (PAP) and D-dimer (DD) values were determined daily in the early postoperative period for 11days. In addition, the course of PAP and DD concentrations was compared with the method of esophagectomy. Of the 28 patients enclosed in the study, 5 died between day 10 and day 34 owing to adult respiratory distress syndrome and septicemia. The PAP and DD concentrations increased in survivors after surgery until day 5 an…

AdultMalemedicine.medical_specialtyTime FactorsFatal outcomeEsophageal Neoplasmsmedicine.medical_treatmentReference range030204 cardiovascular system & hematologySensitivity and SpecificityGastroenterologyFibrin Fibrinogen Degradation Products03 medical and health sciences0302 clinical medicineInternal medicineFibrinolysisD-dimermedicineHumansFibrinolysinPostoperative PeriodSurvival rateAgedalpha-2-AntiplasminRespiratory distressbusiness.industryFibrinolysisMortality rateHematologyGeneral MedicineMiddle AgedPrognosisAntifibrinolytic AgentsSurgeryEsophagectomySurvival RateROC CurveEsophagectomyFemalebusinessBiomarkers030215 immunologyClinical and Applied Thrombosis/Hemostasis
researchProduct

1023 – Therapeutic drug-monitoring of bupropion for depression

2013

Introduction Therapeutic Drug-Monitoring (TDM) for bupropion is limited by bupropion's instability at room temperature and by the absence of a well-defined therapeutic reference range. Further it is unclear to what extent bupropion and its metabolites contribute to therapeutic effects, though hydroxybupropion seems to account for the major antidepressant effects. Aim The aim of this examination was to check if measurement of only hydroxybupropion is useful to guide the antidepressant therapy with bupropion. Methods Hydroxybupropion plasma levels were measured by high performance liquid chromatography with ultra violet detection and related to therapeutic effects measured by the Clinical Glo…

Bupropionmedicine.diagnostic_testbusiness.industryTherapeutic effectReference rangeHydroxybupropionPharmacologyPsychiatry and Mental healthPharmacokineticsTherapeutic drug monitoringAnesthesiamedicineClinical Global ImpressionAntidepressantbusinessmedicine.drugEuropean Psychiatry
researchProduct

Age-Related Reference Ranges for Fetal Foot Length

2000

AIM The aim of this study was to establish age-dependent reference ranges for fetal foot length with gestation as well as for the femur/foot length ratio, based on a mathematical growth model. METHOD In a prospective cross-sectional study of 610 pregnancies with sonographically confirmed gestational age (< 12 weeks' gestation), fetal biometry was performed in addition to measurements of fetal foot length between 12 and 42 completed weeks of gestation. Reference ranges for the fetal foot and for the femur/foot length ratio were constructed with an overall coverage of 90% of the measured data, using a previously established method of determining reference bands for growth parameters. RESULTS …

FetusFootbusiness.industryGestational ageGestational AgeReference rangeGrowth modelAnatomyUltrasonography PrenatalEmbryonic and Fetal DevelopmentCross-Sectional StudiesFetusPregnancyReference ValuesAge relatedHumansGestationMedicineFemaleRadiology Nuclear Medicine and imagingFemurFemurNuclear medicinebusinessFoot (unit)Ultraschall in der Medizin
researchProduct

Childhood Dietary Intake in Italy: The Epidemiological "MY FOOD DIARY" Survey

2019

Promoting a healthy lifestyle during the first years of life is a key strategy for controlling obesity risk in later life

Male0301 basic medicinemedicine.medical_specialtydescriptive observational study; dietary pattern; epidemiology; food record; health; infants; nutrient intake; obesity; survey; toddlersToddlerEpidemiologyDietary pattern030209 endocrinology & metabolismReference rangelcsh:TX341-641Child Nutritional Physiological PhenomenaFood recordDiet RecordsArticle03 medical and health sciences0302 clinical medicineNutrientEnvironmental healthEpidemiologymedicineHumansEarly childhoodObesitytoddlersChildSurveyDietary Reference Values030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryinfantsInfantFeeding BehaviorNutrientsmedicine.diseaseObesityNutrient intakeDiet RecordsDietDescriptive observational studyItalyHealthChild PreschoolFemaleChild Nutritional Physiological PhenomenaEnergy Intakebusinesslcsh:Nutrition. Foods and food supplyFood Science
researchProduct

Low Energy Availability is Difficult to Assess But Outcomes Have Large Impact on Bone Injury Rates in Elite Distance Athletes

2018

We aimed to (a) report energy availability (EA), metabolic/reproductive function, bone mineral density, and injury/illness rates in national/world-class female and male distance athletes and (b) investigate the robustness of various diagnostic criteria from the Female Athlete Triad (Triad), Low Energy Availability in Females Questionnaire, and relative energy deficiency in sport (RED-S) tools to identify risks associated with low EA. Athletes were distinguished according to benchmarks of reproductive function (amenorrheic [n = 13] vs. eumenorrheic [n = 22], low [lowest quartile of reference range; n = 10] versus normal testosterone [n = 14]), and EA calculated from 7-day food and training d…

MaleTriadMedicine (miscellaneous)Physiology0302 clinical medicineBone DensitySurveys and QuestionnairesOrthopedics and Sports MedicineTestosteroneAmenorrheaaineenvaihduntaTestosteroneBone mineralluustoNutrition and DieteticsTriiodothyroninebiologyGeneral MedicineQuartileAthletic InjuriesTriiodothyronineFemaleFemale athlete triadAdultluuntiheys030209 endocrinology & metabolismReference rangemetabolic hormonesBone and Bonesreproductive hormones03 medical and health sciencesYoung AdultmedicineHumansbone healthRED-SAthletesbusiness.industryMalnutritionNutritional RequirementsFemale Athlete Triad Syndrome030229 sport sciencesbiology.organism_classificationmedicine.diseasehormonitSports Nutritional Physiological PhenomenaCross-Sectional StudiesenergiansaantiAthletesbusinessEnergy IntakeEnergy MetabolismHormone
researchProduct

Intrahepatic bile duct dilation and gallbladder hydrops due to a cystic duct stenosis in a 2-month-old boy.

2015

A 2-month-old boy presented with slight diffuse abdominal pain after an uncomplicated pregnancy and perinatal period. Height (62 cm) and weight (5.5 kg) were according to the age. Routine blood tests showed no abnormalities except for a minimal elevation of aspartate aminotransferase to 38 units/L (reference range 5–35 U/L). Primary abdominal ultrasound showed a dilation of the common bile duct and a gallbladder hydrops (figure 1). MR cholangiopancreatography (MRCP) was indicated to detect the cause for these incidental findings. Contrary to normal bile ducts in …

Malemedicine.medical_specialtyAbdominal painCholangiopancreatography Magnetic ResonanceGallbladder diseaseIntrahepatic bile ductsReference rangeConstriction PathologicGallbladder DiseasesGastroenterologyArticleDiagnosis DifferentialInternal medicinemedicineHumansCommon bile ductbusiness.industryGeneral surgeryCystic DuctInfantGeneral Medicinemedicine.diseaseStenosismedicine.anatomical_structureBile Ducts IntrahepaticCystic ductDifferential diagnosismedicine.symptombusinessDilatation PathologicBMJ case reports
researchProduct